Apolipoprotein A1 (APOA1)

What is ApoA?

ApoA(apolipoprotein A) is a protein carrier for HDL. ApoA is considered to be the most informative biomarker for “good cholesterol" and can be used to determine your risk for cardiovascular disease.

Why is it included in the Cardiovascular Axis?

Both HDL cholesterol and ApoA-I are, in most clinical conditions, antiatherogenic-the higher the values, the lower the cardiovascular risk. Your ApoA measurement can be an important predictor of your cardiovascular health.

How can I better understand my results?

High ApoA may be caused by genetic disorders, certain medications, or recent weight loss. Low ApoA may be caused by diabetes, coronary artery disease, Tangier disease (< 25 mg/dL), liver disorders, and certain lifestyle choices such as smoking cigarettes. Because ApoA levels can be an indicator of many deleterious diseases, it is important to consult with your physician if you are concerned with your levels. Aim for levels to fall higher in the normal range.

Males:

Females:

To improve your Apo profile, you can try:

  • Limit foods with added sugar (sweets, jam, sugar-sweetened beverages)
  • Consume fermented dairy products (fermented milk, cheese)
  • Avoid smoking
  • Increase physical activity
  • If you are obese, consider losing weight through a healthy diet and exercise

Where can I learn more?

University of Rochester Medical Center - Apolipoprotein A

Discover Cholesterol Efflux (video) - The importance of ApoA-1 in cholesterol efflux and atherosclerosis


The above is informational content only. None of it is intended as medical or diagnostic advice. Please consult your provider for information or concerns regarding your results

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